Databases of Information on Genetic Diseases in Animals

Canine Genetic Disease Information System (CGDIS)

Dr. Donald Patterson in the Section of Medical Genetics at Penn has developed a computerized database on genetic diseases of dogs, the Canine Genetic Disease Information System (CGDIS). This database in being published by Moseby, and will be released early next year. The database is available in the Section of Medical Genetics for your use. To arrange a time to do so, talk to Dr. Henthorn.

 

Online Mendelian Inheritance in Animals (OMIA)

This is a searchable database, compiled by Prof. Frank Nicholas at the University of Sydney, of references to genetic diseases in many animal species. OMIA is modeled on and complementary to McKusick's Mendelian Inheritance in Man (OMIM). Most entries consist solely of references to publications (without links to abstracts), although some entries contain a brief summary of the disease and how it is inherited. Links to similar diseases in OMIM are included, where appropriate.

 

Inherited diseases in dogs

A searchable database of genetic diseases/conditions of purebred dogs compiled by Dr. David Sargan at the University of Cambridge. The user can search by breed, genetic anomaly, or keyword. A short description is given for each disease, and the inheritance of the disease is discussed if it is known. References are linked to abstracts, mainly through PubMed. Links to similar human diseases in OMIM are also provided.

 

Canine Inherited Disorders Database

From the University of Prince Edward Island and the Canadian Veterinary Medical Association, this site is intended for use by dog owners and breeders as well as veterinarians. The database, while not searchable, is organized by organ system affected and by dog breed. For each disease, the site discusses inheritance (if known), breeds affected, presentation, diagnosis, treatment, and breeding advice. A limited number of references are provided.

CANINE GENETICS INFORMATION
Canine Molecular Genetic Diseases
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Michigan State University
Ulreh V. Mostoskey, DVM
George A. Padgett, DVM
Al W. Stinson, DVM
VetGen LLC, Ann Arbor, Michigan
John C. Duffendack, MBA, MS

CLICK HERE FOR MORE INFORMATION
We require all of our Goldendoodle puppies to have a DNA SAMPLE,  profiled and kept in storage with VETGEN in order to maintain our purchased  genetic health warranty.   This is the ONLY way to either prove or disprove Genetic health issues should one arise during your  purchased warranted time frame.  We  now provide each customer with the  application to submit your puppy's  DNA SAMPLE for storage.    CLICK HERE for DNA STORAGE fees/costs.  VetGen will store a DNA SAMPLE for up to ten years. 
A DNA profiling application can be obtained from us regarding any canine purchased through us, if desired.

Many vets will tell a customer that the health issue/s of their canine is inherited, but there is now a way to verify whether that is true or not true through direct DNA TESTING and profiling.  This also helps the breeder to determine which canine to remove or keep in their breeding program and is of great value to the breeder.  While may people want to play the blame game, now it can be avoided altogether through DNA evidence. 
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AUTHOR: DEE GERRISH
The branch of the canine family tree that includes domestic dogs diverged from that of the gray wolf more than 15,000 years ago. Due to selective breeding by humans throughout history, dogs today exhibit an extremely wide range of body types and behaviors. In fact, dogs exhibit the greatest diversity in body size of any mammalian species.

In their study, researchers explored the genetic basis for size variation among dogs by comparing the DNA of various small dog breeds, including Chihuahuas, Toy Fox Terriers and Pomeranians, to an array of larger dog breeds, including Irish Wolfhounds, Saint Bernards and Great Danes. Their investigation found that variation in one gene — IGF-1, which codes for a protein hormone called insulin-like growth factor 1, is very strongly associated with small stature across all dog breeds studied.

“We have been intrigued by the population structure of dogs, which over the years have been selectively bred, allowing us to more readily analyze the genetic causes of particular traits than is possible in humans,” said the study’s senior author Elaine A. Ostrander, Ph.D., chief of NHGRI’s Cancer Genetics Branch. “Nearly all of what we learn from studying body structure, behavior and disease susceptibility in dogs helps us understand some aspect of human health and biology.”
MORE CAN BE READ ON THIS ARTICLE BY CLICKING HERE!!!

*author & breeder: Dee Gerrish....Goldendoodle World